Subsidiaries

Evogene group (NASDAQ:EVGN, TASE: EVGN) includes independently managed subsidiaries focusing on a defined commercial field with an exclusive license to use our unique solution for product development.

Each subsidiary may utilize the CPB platform capabilities to commercialize products independently or through strategic collaborations. The subsidiaries’ diverse product pipeline mitigates the risk associated with individual development and drive opportunities forward.

Human Health

Human Microbiome

Biomica Mission: Discovery and development of novel therapies for microbiome-related human disorders using computational predictive biology

Milestones

2022

IBD – initiate scale-up for GMP production of drug candidate for IBD

Immuno-oncology – readout from proof-of-concept, first in human study

2023

IBD – clinical batch production of drug candidate for IBD as preparation for Phase 1 clinical trials in USA

Immuno-oncology – pre-IND meeting with FDA

Human Health

Medical Cannabis

Canonic Mission: Commercialize effective, precise and stable medical cannabis products, based on decoding plant genetics, for optimized therapeutic effect

Milestones

2022

MetaYield – commercial launch of second- generation products in Israel

Precise – collect user data for clinical indications to support commercial launch in 2023

2023

MetaYield – commercial launch of first product in Europe

Precise – commercial launch of first product in Israel

Agriculture

Ag-Chemicals

AgPlenus Mission: Design of next-generation effective and sustainable crop protection products by leveraging predictive biology and chemistry

Milestones

2022

New MoA herbicides – enter an additional collaboration agreement

New MoA herbicide – expand data package for APTH1, AgPlenus’ leading new MoA protein for the development of novel herbicides

2023

New MoA herbicides – reach milestone in one of the ongoing collaborations

New MoA fungicide – initial greenhouse readouts

Agriculture

Ag Biologicals

Lavie Bio Mission: Improve food quality, sustainability and agriculture productivity through
microbiome based ag-biologicals technology and products

Milestones

2022

Bio-stimulants – build infrastructure for scale-up in ‘result™’ sales for spring wheat in 2023

Bio-fungicides – file for regulatory approval for leading product candidate LAV311 for fruit rot

2023

Bio-stimulants – ‘result™’ product sales expansion in US and Canada for spring wheat

Bio-fungicides - file for regulatory approval for leading product candidate LAV321 or LAV322 for downy mildew

Industrial Applications

Castor Oil Production

Castera Mission: Provide farmers with the most advanced Castor seeds & Ag-service solutions